2-{(E)-4-[4-(Trifluoromethyl)phenoxy]but-2-enyloxy}phenyl N-methylcarbamate
نویسندگان
چکیده
In the title compound, C19H18F3NO4, which was designed and synthesized as a dual-site inhibitor of insect AChE (acetyl-cholinesterase), the dihedral angle between the methyl-carbamate group and the benzene ring is 72.47 (6)°. In the crystal, inversion dimers are linked by pairs of N-H⋯O hydrogen bonds.
منابع مشابه
3-Methyl-5-phenoxy-1-phenyl-1H-pyrazole-4-carbaldehyde
In the title compound, C(17)H(14)N(2)O(2), the pyrazole ring makes dihedral angles of 73.67 (4) and 45.99 (4)°, respectively, with the adjacent phenyl and phen-oxy rings. In the crystal, there are no classical hydrogen bonds, but a weak C-H⋯π inter-action is observed.
متن کامل2-[5-Methyl-2-(propan-2-yl)phenoxy]-N′-{2-[5-methyl-2-(propan-2-yl)phenoxy]acetyl}acetohydrazide
The complete mol-ecule of the title compound, C(24)H(32)N(2)O(4), is generated by a crystallographic inversion center. The 1,2-diethyl-hydrazine moiety is nearly planar, with a maximum deviation of 0.024 (1) Å, and is inclined at a dihedral angle of 54.20 (4)° with the phenyl ring. In the crystal, [001] chains are formed, with adjacent mol-ecules in the chain linked by pair of inter-molecular N...
متن کامل2-Methylcarbamoyl-4-{4-[3-(trifluoromethyl)benzamido]phenoxy}pyridinium 4-methylbenzenesulfonate monohydrate
The asymmetric unit of the title compound, C(21)H(17)F(3)N(3)O(3) (+)·C(7)H(7)O(3)S(-)·H(2)O, contains two formula units. In one of the cations, the pyridinium and trifluoro-methyl benzene rings form dihedral angles of 87.42 (8) and 45.92 (8)°, respectively, with the central benzene ring [79.56 (8) and 43.52 (8)° in the other cation]. In the crystal structure, N-H⋯O, O-H⋯O and C-H⋯O hydrogen bo...
متن کامل1-(Pyridin-2-yl)-2-[2-(trifluoromethyl)benzyl]-3-[2-(trifluoromethyl)phenyl]propan-1-one
The title compound, C(23)H(17)F(6)NO, crystallizes with two mol-ecules in the asymmetric unit. The mol-ecules assume an approximate propellar shape, with the three aromatic rings being bent with respect to the plane formed by the C atoms that are connected to the methine C atom [dihedral angles: pyridyl 67.49 (3)°, phenyl 56.82 (4)° and phenyl 77.21 (6)° in one mol-ecule, and corresponding angl...
متن کامل2-Phenoxy-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-one
The triazoloquinazole ring system in the title compound, C(15)H(10)N(4)O(2) is approximately planar (r.m.s. deviation = 0.035 Å). The phenyl ring of the phen-oxy substitutent is aligned at 59.3 (1)° with respect to this ring system. In the crystal, two mol-ecules are linked about a center of inversion by a pair of N-H⋯O hydrogen bonds, generating a dimer.
متن کامل